From Peptides to PRP

“Biohacking” may sound like a buzzword reserved for tech gurus and wellness radicals, but chances are, you’re already incorporating it into your esthetics practice—whether you realize it or not. 

At its core, biohacking is the practice of making small, intentional changes to improve physical and mental performance. It spans everything from intermittent fasting to boost energy, to plunging into freezing water to boost circulation, to tracking sleep with high-tech wearables. But biohacking has also quietly entered the world of skin care—and it’s transforming how we think about aging, inflammation, and overall skin function. 

So, what does this look like in the treatment room? Let’s explore four main categories of skin-focused biohacking. 

Topical Biohacking 

Modern skin care ingredients do more than moisturize—they communicate. Adaptogenic ingredients like ashwagandha and reishi mushroom help skin adapt to stress, while peptides such as copper (GHK-Cu) and Matrixyl (a synthetic peptide) signal collagen production and cellular repair. Bioenergetic ingredients like NAD+, resveratrol, and stem cell derivatives work at the mitochondrial level, improving not just how skin looks, but how it functions. 

Internal Biohacking 

Skin health often reflects what’s going on inside. Supplements like collagen peptides, hyaluronic acid, and ceramides support hydration and elasticity. Gut health—managed through probiotics, anti-inflammatory diets, and even intermittent fasting—can have a direct impact on inflammatory skin conditions like acne and rosacea. Collaborating with nutrition-savvy professionals or offering simple wellness tips can enhance client results. 

Device-Based Biohacking 

Red light therapy is one of the most science-backed tools1 for skin rejuvenation, stimulating ATP production and cellular repair. Cold therapies, like cryotherapy or ice rolling, reduce inflammation and promote circulation. Devices like microcurrent tools and neurocosmetic products train facial muscles and influence skin’s nervous system—helping to lift, tone, and regulate skin responses. 

Advanced Biohacking 

At the cutting edge, advanced therapies like exosomes, PRP, and genetic testing promise personalized, regenerative results. These methods should always be performed or guided by trained professionals, and represent the next frontier in skin care science. 

Whether you're layering red light into facials or recommending probiotics for clearer skin, you’re already biohacking—just with a professional twist. The key is staying educated and evidence-based, and empowering your clients to become active participants in their skin health.